SCOPE 20

Methods for Assessing the Effects of Chemicals
on Reproductive Functions

Edited by

Velimir B. Vouk - National Institute of Environmental Health Sciences,
Research Triangle Park, North Carolina, USA

and

Patrick J. Sheehan - Institute of Environmental Medicine, New York University
Medical Centre, New York, USA

Prepared by

Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC)

Published on behalf of the

Scientific Committee on Problems of the Environment (SCOPE)

of the

International Council of Scientific Unions (ICSU)

by

John Wiley & Sons

Chichester, New York, Brisbane, Toronto

1983

Click on a chapter number to open pdf.

Title Pages
Table of Contents
Foreword by G.F. White and M.J. Mercier
Preface
Scientific Group on Methodologies for the Safety Evaluation of Chemicals Participants of the Workshop

PART A JOINT REPORT

1. Introduction, General Conclusions and Recommendations
2. Mammals: Reproductive Function of Females
3. Mammals: Reproductive Function of Males
4. Vertebrates Other Than Mammals
5. Invertebrates
6. Higher Plants, Algae and Microorganisms
Annex: General Aspects of Test Procedures in Reproduction Toxicology

PART B CONTRIBUTED PAPERS

Adverse Effects of Environmental Agents on Mammalian Female Reproduction - W. LeRoy Heinrichs and Merrit Gadallah
Adverse Effects of Chemicals on Male Reproductive Function in Mammals - Thaddeus Mann and Cecilia Lutwak-Mann
Laboratory Aspects of Reproductive Toxicology - Robert L. Dixon
Effects of Chemicals on Reproductive Function - I.V. Sanockij
Effects of Chemicals on Reproductive Functions of Mammals: Mechanisms of Cell Injury and Adaptive Responses - Linda R. Wudl and Michael I. Sherman
Epidemiological Approach to Human Reproductive Failure Assessment - Dorothy Warburton, Zena Stein and Jennie Kline
Laboratory Methods for Evaluating and Predicting Specific Reproductive Dysfuntions: Oogenesis and Ovulation - Donald R. Mattison and Griff T. Ross
Techniques for Detecting and Evaluating Abnormalities in Testicular Function - Jeffrey B. Kerr and David M. de Kretser
Morphological and Chemical Methods of Semen Analysis for Quantitating Damage to Male Reproductive Function in Man - Rune Eliasson
The Mammalian Embryo and Fetus in vitro - D.A.T. New
Methods for Evaluating and Predicting Human Fetal Metabolism and Development - J.E. Jirasek
Experimental Methods in Embryotoxicity Risk Assessment - Richard Jelinek and Otakar Marhan
Perinatal Exposure and Teratological End-points: Some Principles and Possibilities - Richard Doherty
Appraisal of Reproductive Failure in Wildlife - J.E. Kihlstrom
Methods for Assessment of the Effects of Pollutants on Avian Reproduction - David B. Peakall
Methods to Test and Assess Effects of Chemicals on Reproduction in Fish - Edward M. Donaldson and Eberhard Scherer
Assessment of the Effects of Chemicals on the Reproductive Functions of Reptiles and Amphibians - AnnLouise Martin
Methods for the Assessment of the Effects of Chemicals on the Reproductive Function of Insects - V. Landa, B. Bennettova, I. Gelbic, S. Matolin and T. Soldan
Methods for Assessing the Effects of Chemicals on Reproductive Function in Marine Molluscs -
D.R. Dixon
Methods for Assessing the Effects of Chemicals on Reproduction in Marine Worms - Bertil Akesson
Methods for Assessing the Effects of Chemicals on Reproductive Function in Certain Invertebrates: Some Principles and Recommendations - K.G. Davey, A.S.M. Saleuddin, C.G.H. Steel and
R.A. Webb

Methods for Assessing the Effects of Chemicals on Reproduction in Higher Plants - P.L. Pfahler and H.F. Linskens
Methods for Assessing Effects of Chemicals of Algal Reproduction - Arne Jensen
Methods for Assessing the Effects of Chemicals on the Reproductive Functions of Microorganisms -
J. Howard Slater

Subject Index